Toward a biochemical classification of depressive disorders, V: Heterogeneity of unipolar depressions.
Am J Psychiatry
; 139(4): 471-5, 1982 Apr.
Article
em En
| MEDLINE
| ID: mdl-7065292
ABSTRACT
The authors found that the mean urinary level of 3-methoxy-4-hydroxyphenylglycol (MHPG) was significantly lower in 20 patients with bipolar manic-depressive or schizoaffective depressions than in either 50 patients with unipolar depressions or 26 age- and sex-matched control subjects. In contrast, the mean MHPG levels in the total group of patients with unipolar depressions and in any subgroup defined by Research Diagnostic Criteria (RDC) were not significantly different from control values. However, examination of the distribution of urinary MHPG levels in patients with unipolar depressions in relation to other recent findings by the authors' collaborative research group suggested the existence of at least three biochemical subtypes of unipolar depressions that may, in part, be differentiated on the basis of urinary MHPG levels.
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Base de dados:
MEDLINE
Assunto principal:
Transtorno Depressivo
/
Glicóis
/
Metoxi-Hidroxifenilglicol
Limite:
Adult
/
Humans
Idioma:
En
Ano de publicação:
1982
Tipo de documento:
Article