Electron microscopic and pharmacologic evidence for a functional adrenergic innervation of the smooth musculature in the human fallopian tube.
Brain Res Bull
; 9(1-6): 695-9, 1982.
Article
em En
| MEDLINE
| ID: mdl-7172043
ABSTRACT
Triple fixation for electron microscopy of the isthmic region of the human Fallopian tube distinguished adrenergic nerve terminals through their content of synaptic vesicles with a diameter of 50-60 nm. Non-vascular adrenergic nerves were found both outside and within smooth muscle bundles. Adrenergic varicosities, partly devoid of their Schwann cell ensheathing, frequently approached the smooth muscle cells within a distance of about 200 nm, and sometimes as close as 60-100 nm. These close contacts often occupied a considerable area of the naked varicosity. Electrical field stimulation of adrenergic nerves in the isthmic smooth muscle preparations in vitro induced an alpha-receptor mediated, frequency-dependent contractile response. The results show that the sympathetic nerves in the human Fallopian tube are able to exert a motor control of its smooth musculature, and may thus be involved in local functions essential for the normal fertilization process.
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Base de dados:
MEDLINE
Assunto principal:
Fibras Adrenérgicas
/
Tubas Uterinas
/
Músculo Liso
Limite:
Adult
/
Female
/
Humans
/
Middle aged
Idioma:
En
Ano de publicação:
1982
Tipo de documento:
Article