Local synthesis of CSF immunoglobulins. A neuroimmunological classification.
J Neurol Sci
; 51(3): 361-70, 1981 Sep.
Article
em En
| MEDLINE
| ID: mdl-7276983
ABSTRACT
The relationship between serum and CSF IgG has been analysed (1) In patients with a normal CSF concentration of albumin, no correlation can be demonstrated between serum IgG and CSF IgG. (2) In cases where the CSF albumin concentration is elevated (i.e. transudation), local synthesis of IgG can be determined by reference of the degree of transudation of albumin and the serum IgG concentration. The combination of local IgG synthesis and transudation (meningitic pattern) is common. Most pure transudates are of "non-inflammatory" type. A very simple formula is proposed which evaluates the relationship between local and general immunity in all neurological diseases.
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Base de dados:
MEDLINE
Assunto principal:
Imunoglobulinas
/
Doenças do Sistema Nervoso
Limite:
Humans
Idioma:
En
Ano de publicação:
1981
Tipo de documento:
Article