A method for the separation and determination of neutral compounds in postmortem tissues.
J Anal Toxicol
; 5(4): 162-4, 1981.
Article
em En
| MEDLINE
| ID: mdl-7278153
ABSTRACT
A convenient method for the extraction of neutral drugs in necrotic tissues is described. The procedure includes the use of hot dilute acid for isolating neutrals from tissue extract residues and of internal standard to facilitate quantitative and recovery measurement of the drugs by gas chromatography. The recovery of seven neutral compounds from liver ranged from 47.0% to 89.3%. The limit of detection of these drugs were 0.5 to 1.0 mg/kg.
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Base de dados:
MEDLINE
Assunto principal:
Preparações Farmacêuticas
Limite:
Humans
Idioma:
En
Ano de publicação:
1981
Tipo de documento:
Article