Enzyme studies and neonatal brain damage.
Acta Paediatr Scand
; 70(5): 743-9, 1981 Sep.
Article
em En
| MEDLINE
| ID: mdl-7324924
ABSTRACT
The authors report a double-blind study of 57 full-term newborn infants prospectively subjected to clinical, electroencephalographical, blood and cerebrospinal fluid, and developmental examinations. Four enzymatic activities were measured in blood and CSF aminotransferase (ASAT), creatine kinase (CK), lactate dehydrogenase (LD) and hydroxybutyrate dehydrogenase (HBD). Close relationships of enzymatic levels with psychomotor outcome are reported. In blood, ASAT and CL seemed to be the most important determinations, allowing threshold-values to be suggested. In CSF, LD and HBD were the determinations the most closely related to psychomotor events at age one. This method seems to be of theoretical as well as practical importance in evaluating neonatal brain injury.
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Base de dados:
MEDLINE
Assunto principal:
Dano Encefálico Crônico
/
Ensaios Enzimáticos Clínicos
Tipo de estudo:
Clinical_trials
/
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Humans
/
Newborn
Idioma:
En
Ano de publicação:
1981
Tipo de documento:
Article