The role of T-agglutinin in the disappearance of erythrocytes artificially aged by desialylation.
Mech Ageing Dev
; 12(1): 53-63, 1980 Jan.
Article
em En
| MEDLINE
| ID: mdl-7354664
ABSTRACT
The chance discovery of two mouse strains, one with and one without a high presence of serum T-agglutinin, permitted the investigation of the role of this antibody in the disappearance of desialylated erythrocytes, which may be regarded as a model for ageing. The proportional relationship between the quantity of sialic acid removed and the diminution of half-life is not affected by the presence or absence of T-agglutinin. Opsonization by T-agglutinin would therefore appear to be an improbable mechanism. Other possible theories are discussed.
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Base de dados:
MEDLINE
Assunto principal:
Ácidos Siálicos
/
Imunoglobulina M
/
Aglutininas
/
Envelhecimento Eritrocítico
/
Hemaglutininas
Limite:
Animals
Idioma:
En
Ano de publicação:
1980
Tipo de documento:
Article