The structural events associated with the attachment of complement components to cell membranes in reactive lysis.
Immunology
; 35(2): 205-12, 1978 Aug.
Article
em En
| MEDLINE
| ID: mdl-750370
ABSTRACT
Electron microscopic study of the events occurring at the cell membrane during reactive lysis by complement, showed that a foliaceous particle was formed at the C5b-7 stage, that enlarged to a particle with a variable number of arms at the C5b-8 stage. Up to this point, no typical complement lesions were found. At the C5b-9 stages, the particles were completely converted to typical complement lesions, i.e. hollow cylinders projecting from the cell membrane and partly penetrating it. C5b-9 complexes assembled in the fluid phase did not show the typical structure of the lesions, but were amorphous masses of fibres.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Proteínas do Sistema Complemento
/
Membrana Eritrocítica
/
Eritrócitos
/
Hemólise
Tipo de estudo:
Risk_factors_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
1978
Tipo de documento:
Article