Effective immune protection of pigs against cysticercosis.
Vet Immunol Immunopathol
; 45(1-2): 127-37, 1995 Mar.
Article
em En
| MEDLINE
| ID: mdl-7604530
ABSTRACT
A scolex protein antigen (SPA) was prepared from cysticerci of Taenia solium obtained from naturally infected pigs. Yorkshire pigs were vaccinated with SPA plus incomplete Freund's adjuvant (IFA) or with SPA plus Corynebacterium parvum (CP). Controls were given IFA plus phosphate-buffered saline (PBS) or CP plus PBS. All animals were given three subcutaneous injections at 20-day intervals. Ten days after the third injection, the pigs were fed with 10(4) viable eggs of T. solium. All pigs developed a delayed type hypersensitivity, and a transient eosinophilia after the first dose of vaccine. High titers of specific antibodies were detected in the sera of vaccinated animals and in infected controls. A protection level of 71.43% was recorded in animals vaccinated with SPA plus IFA and of 75.00% in those vaccinated with SPA plus CP.
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Base de dados:
MEDLINE
Assunto principal:
Doenças dos Suínos
/
Cisticercose
/
Proteínas de Helminto
/
Vacinação
/
Cysticercus
Limite:
Animals
Idioma:
En
Ano de publicação:
1995
Tipo de documento:
Article