[Effects of propofol in patients in status epilepticus of various origins. Electroencephalographic analysis]. / Effetti del propofol in pazienti in stato di male epilettico di varia origine. Analisi elettroencefalografica.

ABSTRACT

The authors discuss the effect of propofol administered to epileptic patients in intensive care. Several reports have attributed and antiepileptic effect to this drug, whereas a similar number have correlated it to epileptogenic manifestations of various types. Three "typical" cases of epilepsy were studied chronic postoperative, chronic and acute post-traumatic. EEG patterns were analysed following continuous administration, using a bolus and using varying doses of the drug itself. Propofol appears to modify EEG patterns in a positive manner and is therefore confirmed as being useful in the sedation of epileptic patients in intensive care.