A comparison of low vs standard dose intramuscularly administered hepatitis B vaccine.
J Assoc Physicians India
; 42(6): 461-2, 1994 Jun.
Article
em En
| MEDLINE
| ID: mdl-7852229
ABSTRACT
In a randomised, controlled, single-blind trial we compared different doses of a yeast-derived recombinant hepatitis B vaccine a low dose intramuscular (i.m.) regimen (using 2 micrograms at first followed by 1 microgram each at 1, 2 and 6 months) with the standard dose (10 micrograms each at 0, 1 and 6 months) for post vaccination anti-HBs seropositivity. At the end of 7 months, only 78% of volunteers on the low dose (n = 77) tested positive for anti-HBs whereas 100% of volunteers on the standard dose (n = 43) were seropositive. Therefore, low dose regimen is not satisfactory for primary HBV vaccination.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Vacinas contra Hepatite B
/
Hepatite B
Tipo de estudo:
Clinical_trials
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
1994
Tipo de documento:
Article