The GRB family of SH2 domain proteins.
Prog Biophys Mol Biol
; 62(3): 223-44, 1994.
Article
em En
| MEDLINE
| ID: mdl-7892504
ABSTRACT
The cloning of SH2 domain proteins based on their binding to growth factor receptors is a powerful technique to elucidate new signaling pathways. In some cases the function of these proteins has been quickly ascertained while in others the answers still elude us. However the major power of the technique is its ability to identify novel signaling cascades that can emanate from tyrosine kinases. The challenge is to define the nature of these signaling cascades.
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Base de dados:
MEDLINE
Assunto principal:
Transdução de Sinais
/
Proteínas
/
Estrutura Terciária de Proteína
/
Receptores de Fatores de Crescimento
Tipo de estudo:
Prognostic_studies
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
1994
Tipo de documento:
Article