Evidence for an intermediate in the enzymatic formation of uroporphyrinogen III.
Bioorg Med Chem
; 2(3): 153-68, 1994 Mar.
Article
em En
| MEDLINE
| ID: mdl-7922129
ABSTRACT
Evidence for an azafulvene intermediate in the enzymatic formation of Uroporphyrinogen III has been obtained. Using conditions to slow down the enzyme activity (high pH, low temperature), the transient species was trapped with ammonium ions as aminomethylbilane and with sodium borohydride as methylbilane, and observed by 13C-NMR.
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Base de dados:
MEDLINE
Assunto principal:
Uroporfirinogênios
Idioma:
En
Ano de publicação:
1994
Tipo de documento:
Article