An acquired Robertsonian 13;15 translocation in acute myelogenous leukemia (M5b).
Int J Hematol
; 59(2): 131-5, 1994 Feb.
Article
em En
| MEDLINE
| ID: mdl-8018906
ABSTRACT
A 43-year-old male developed acute myelogenous leukemia (AML, M5b) with an acquired Robertsonian 13;15 translocation. He did not achieve complete remission after sequential intensive induction chemotherapy and he died 13 months later. We reviewed 7 patients with this translocation reported in the literature. Acquired Robertsonian translocations are rare, but could represent an important event in the tumorigenesis of hematologic malignancies.
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Base de dados:
MEDLINE
Assunto principal:
Translocação Genética
/
Cromossomos Humanos Par 13
/
Cromossomos Humanos Par 15
/
Leucemia Mieloide Aguda
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Ano de publicação:
1994
Tipo de documento:
Article