Induction of aerial mycelium formation in a bld mutant of Streptomyces tendae by borrelidin--a macrolide antibiotic.
FEMS Microbiol Lett
; 114(1): 41-5, 1993 Nov 15.
Article
em En
| MEDLINE
| ID: mdl-8293958
ABSTRACT
In a screening programme for substances with morphogenic effects on the nikkomycin producer strain Streptomyces tendae Tü 901 we identified a metabolite, which induced aerial mycelium formation in the bld mutant Tü 901/S 2566-EM 1. By using a HPLC UV/Vis absorbance spectral library we could confirm that this compound was identical with the macrolide antibiotic borrelidin. 100 ng borrelidin/paperdisc were sufficient to show an evident morphological effect.
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Base de dados:
MEDLINE
Assunto principal:
Streptomyces
/
Antibacterianos
Idioma:
En
Ano de publicação:
1993
Tipo de documento:
Article