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A preliminary open trial on interferon stimulator (SNMC) derived from Glycyrrhiza glabra in the treatment of subacute hepatic failure.
Acharya, S K; Dasarathy, S; Tandon, A; Joshi, Y K; Tandon, B N.
Afiliação
  • Acharya SK; Department of Gastroenterology & Human Nutrition, All India Institute of Medical Sciences, New Delhi.
Indian J Med Res ; 98: 69-74, 1993 Apr.
Article em En | MEDLINE | ID: mdl-8344734
ABSTRACT
The efficacy of the interferon stimulator named Stronger Neo Minophagen-C (SNMC) derived form the plant G. glabra was studied at a dose of 40 or 100 ml daily for 30 days followed by thrice weekly intravenously for 8 wk in 18 patients of subacute hepatic failure due to viral hepatitis. The survival rate amongst these patients was 72.2 per cent, as compared to the earlier reported rate of 31.1 per cent in 98 patients who received supportive therapy (P < 0.01). Death in four of the five patients was due to associated infections leading to hepatorenal failure and terminal coma. Further studies are necessary to standardize the dose and duration of therapy with SNMC in subacute hepatic failure.
Assuntos
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Base de dados: MEDLINE Assunto principal: Ácido Oleanólico / Plantas Medicinais / Indutores de Interferon / Falência Hepática / Cisteína / Glicina / Glycyrrhiza Limite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 1993 Tipo de documento: Article
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Base de dados: MEDLINE Assunto principal: Ácido Oleanólico / Plantas Medicinais / Indutores de Interferon / Falência Hepática / Cisteína / Glicina / Glycyrrhiza Limite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 1993 Tipo de documento: Article