Comparative effect of nifedipine and S-adenosylmethionine, singly and in combination on experimental rat liver cirrhosis.
Life Sci
; 52(20): PL217-20, 1993.
Article
em En
| MEDLINE
| ID: mdl-8483386
ABSTRACT
An experimental rat liver cirrhosis, by means of carbon tetrachloride and ethanol during 8 weeks, was employed to assay the effect of Nifedipine (a calcium antagonist blocker), S-Adenosylmethionine (a precursor of glutathione); singly and in combination on rat liver cirrhosis. A slight decrease of cirrhosis (N.S.) was observed with the pharmacological therapy employed singly. The combination therapy (Nifedipine+S-Adenosylmethionine) significantly inhibited liver cirrhosis (p < 0.01).
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Base de dados:
MEDLINE
Assunto principal:
S-Adenosilmetionina
/
Nifedipino
/
Cirrose Hepática Experimental
Limite:
Animals
Idioma:
En
Ano de publicação:
1993
Tipo de documento:
Article