Convulsive properties of N-(3,5-dimethoxy-4-propoxyphenyl-ethyl) aziridine and their influencing by diazepam and triazolam.
Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove
; 38(2): 85-8, 1995.
Article
em En
| MEDLINE
| ID: mdl-8584863
ABSTRACT
Convulsive activity of N-(3,5-dimethoxy-4-propoxy-phenyl-ethyl)-aziridine (FAZ-4), a newly synthetized aziridine compound was studied in rats. There is a lack of tonic component of major paroxysm in comparison with the classical convulsive agent pentylenetetrazol. This effect of FAZ-4 is probably due to the forebrain mechanism without the midbrain involvement. Both anticonvulsants tested suppressed seizures in a different manner, however triazolam exerted stronger anticonvulsive activity than the same dose of diazepam did.
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Base de dados:
MEDLINE
Assunto principal:
Convulsões
/
Aziridinas
/
Triazolam
/
Diazepam
/
Anticonvulsivantes
Limite:
Animals
Idioma:
En
Ano de publicação:
1995
Tipo de documento:
Article