Macrosphelide, a novel inhibitor of cell-cell adhesion molecule. II. Physiochemical properties and structural elucidation.
J Antibiot (Tokyo)
; 49(1): 95-8, 1996 Jan.
Article
em En
| MEDLINE
| ID: mdl-8609095
ABSTRACT
New anticell-adherence compounds, macrosphelides A and B, were isolated from the fermentation broth of Microsphaeropis sp. FO-5050, and their structures were elucidated by spectroscopic methods and chemical transformations. Macrosphelides A (M.W. 342, C16H22O8) and B (M.W. 340, C16H20O8) with three esters in their molecules were classified as 16-membered macrocyclic compounds. Macrosphelide B was found to be a corresponding oxidative product of macrosphelide A at the C-14 position.
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Base de dados:
MEDLINE
Assunto principal:
Adesão Celular
/
Antibacterianos
Idioma:
En
Ano de publicação:
1996
Tipo de documento:
Article