The addition of aminoacids and phosphate to hemodiafiltration solutions in newborns with hyperammonemic coma.
Clin Nephrol
; 46(1): 64-6, 1996 Jul.
Article
em En
| MEDLINE
| ID: mdl-8832155
A child with carbamyl-phosphate-synthetase defect who died after prolonged continuous hemodiafiltration in deep coma proved to have high aminoacid losses despite aminoacid infusion. We think that this results from high small-solute clearance during hemodialysis. In order to prevent these inevitable catabolic side-effects we decided to add aminoacids to the dialysate and substitution fluid in these children with metabolic diseases. Additionally we propose to add phosphate in order to avoid depletion. The aim is to achieve anabolic or at least non-catabolic hemodiafiltration.
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Base de dados:
MEDLINE
Assunto principal:
Fosfatos
/
Soluções para Diálise
/
Hemodiafiltração
/
Coma
/
Aminoácidos
/
Amônia
Limite:
Female
/
Humans
/
Newborn
Idioma:
En
Ano de publicação:
1996
Tipo de documento:
Article