Inhibition of ferrous-induced lipid peroxidation by dipyridamole, RA-642 and mopidamol in human lung tissue.
Gen Pharmacol
; 27(5): 855-9, 1996 Jul.
Article
em En
| MEDLINE
| ID: mdl-8842690
ABSTRACT
1. The in vitro production of ferrous-induced lipid peroxidation was 5.71 times higher in rat lung tissue than in human lung membranes. 2. The pyrimido-pyrimidine derivative RA-642 shows a more potent inhibition of ferrous-induced lipid peroxidation than dipyridamole; mopidamol had no effect. All the compounds showed higher anti-peroxidative effect in rat than in human lung tissue.
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Base de dados:
MEDLINE
Assunto principal:
Pirimidinas
/
Compostos Ferrosos
/
Peroxidação de Lipídeos
/
Dipiridamol
/
Pulmão
/
Mopidamol
/
Antioxidantes
Limite:
Adult
/
Aged
/
Animals
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
1996
Tipo de documento:
Article