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Regional subacute cranial neuropathies following internal carotid cisplatin infusion.
Alderson, L M; Noonan, P T; Choi, I S; Henson, J W.
Afiliação
  • Alderson LM; Neurology Service, Massachusetts General Hospital, Boston, USA.
Neurology ; 47(4): 1088-90, 1996 Oct.
Article em En | MEDLINE | ID: mdl-8857752
The inferolateral trunk arises from the internal carotid artery at C-4 and provides vascular supply to cranial nerves III to VI. We report a patient who developed neuropathies of cranial nerves III, V1-3, and VI, 48 hours after infusion of cisplatin into the right internal carotid artery for an anaplastic oligoastrocytoma. The clinical and radiographic findings implicated direct toxicity to nerves in the distribution of the inferolateral trunk. We found additional cases by review of published brain tumor chemotherapy trials, thus identifying a novel, toxic neurovascular mechanism for injury to cranial nerves III to VI.
Assuntos
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Base de dados: MEDLINE Assunto principal: Cisplatino / Doenças dos Nervos Cranianos Tipo de estudo: Prognostic_studies Limite: Adult / Humans / Male Idioma: En Ano de publicação: 1996 Tipo de documento: Article
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Base de dados: MEDLINE Assunto principal: Cisplatino / Doenças dos Nervos Cranianos Tipo de estudo: Prognostic_studies Limite: Adult / Humans / Male Idioma: En Ano de publicação: 1996 Tipo de documento: Article