Quantification of intrahepatic portosystemic shunting after placement of a transjugular intrahepatic portosystemic shunt.
J Vasc Interv Radiol
; 7(2): 263-7, 1996.
Article
em En
| MEDLINE
| ID: mdl-9007808
ABSTRACT
PURPOSE:
To quantify portosystemic shunting and hepatic portal perfusion after placement of a transjugular intrahepatic portosystemic shunt (TIPS). MATERIALS ANDMETHODS:
Technetium-99m macroaggregated albumin (MAA) was injected directly into the portal veins of nine asymptomatic patients 3 months after TIPS placement. Portosystemic shunting was quantified by comparing counts in the lungs with those in the liver. One cirrhotic patient and one healthy patient who received portal MAA injections were used as controls.RESULTS:
No portosystemic shunting was found in the healthy patient. In the cirrhotic control patient, 77% of the injected activity was in the lungs. Patients with portosystemic shunts had even more activity in the lungs. Even stenotic shunts diverted greater than 80% of portal blood flow systemically. Flow through the TIPS ranged from 84% to 100% (average, 93%); these fractions of flow correlated inversely with portosystemic pressure gradients.CONCLUSION:
Cirrhotic livers may divert much of the portal blood systemically before TIPS placement. Afterward, this proportion rises, and most portal flow is diverted into the pulmonary circulation.
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Base de dados:
MEDLINE
Assunto principal:
Sistema Porta
/
Agregado de Albumina Marcado com Tecnécio Tc 99m
/
Derivação Portossistêmica Transjugular Intra-Hepática
/
Fígado
/
Cirrose Hepática
Limite:
Humans
Idioma:
En
Ano de publicação:
1996
Tipo de documento:
Article