[Splenectomy in osteomyelofibrosis. Indications and outcome]. / Splenektomie bei Osteomyelofibrose. Indikationen und Ergebnisse.
Chirurg
; 67(10): 1016-9, 1996 Oct.
Article
em De
| MEDLINE
| ID: mdl-9011420
ABSTRACT
Osteomyelofibrosis is a myeloproliferative disorder in which fibrosis and sclerosis finally lead to bone marrow obliteration. Liver and spleen compensate for bone marrow loss with extramedullary hematopoiesis. In some patients the resulting splenomegaly causes severe symptoms such as local compression, thrombocytopenia and hemolytic anemia. In such patients, splenectomy is the only promising treatment, although it represents a significant risk.
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Base de dados:
MEDLINE
Assunto principal:
Esplenomegalia
/
Mielofibrose Primária
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
De
Ano de publicação:
1996
Tipo de documento:
Article