The effect of ulinastatin on cutaneous microcirculation during inhalation of 100% oxygen in a rabbit ear chamber.
In Vivo
; 11(2): 173-7, 1997.
Article
em En
| MEDLINE
| ID: mdl-9179612
ABSTRACT
This study aims to investigate the effects of ulinastatin, a human urinary trypsin inhibitor, on the cutaneous microcirculation during inhalation of 100% oxygen in the rabbit. Twenty-one rabbits having a rabbit ear chamber (REC), were divided into 2 groups 11 rabbits without ulinastain treatment (Group C) and 10 rabbits with ulinastatin (Group U). After air inhalation, the inspired gas was changed to 100% oxygen. In Group U, 50,000 units of ulinastatin were administered before changing the concentration of inspired gas. The results suggests that ulinastatin may be useful for maintaining the cutaneous microcirculation during inhalation of 100% oxygen.
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Base de dados:
MEDLINE
Assunto principal:
Oxigênio
/
Glicoproteínas
/
Inibidores da Tripsina
/
Orelha
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
1997
Tipo de documento:
Article