Production of recombinant proteins by methylotrophic yeasts.
Curr Opin Biotechnol
; 8(5): 554-60, 1997 Oct.
Article
em En
| MEDLINE
| ID: mdl-9353229
ABSTRACT
The methylotrophic yeasts Hansenula polymorpha, Pichia pastoris and Candida boidinii have been developed as production systems for recombinant proteins. The favourable and most advantageous characteristics of these species have resulted in an increasing number off biotechnological applications. As a consequence, these species--especially H. polymorpha and P. pastoris--are rapidly becoming the systems of choice for heterologous gene expression in yeast. Recent advances in the development of these yeasts as hosts for the production of heterologous proteins have provided a catalogue of new applications, methods and system components.
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Base de dados:
MEDLINE
Assunto principal:
Pichia
/
Proteínas Recombinantes
/
Candida
/
Clonagem Molecular
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
1997
Tipo de documento:
Article