Glia, neurons, and axon pathfinding during optic chiasm development.
Curr Opin Neurobiol
; 7(5): 647-53, 1997 Oct.
Article
em En
| MEDLINE
| ID: mdl-9384544
ABSTRACT
The importance of vision in the behavior of animals, from invertebrates to primates, has led to a good deal of interest in how projection neurons in the retina make specific connections with targets in the brain. Recent research has focused on the cellular interactions occurring between retinal ganglion cell (RGC) axons and specific glial and neuronal populations in the embryonic brain during formation of the mouse optic chiasm. These interactions appear to be involved both in determining the position of the optic chiasm on the ventral diencephalon (presumptive hypothalamus) and in ipsilateral and contralateral RGC axon pathfinding, development events fundamental to binocular vision in the adult animal.
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Base de dados:
MEDLINE
Assunto principal:
Quiasma Óptico
/
Axônios
/
Neuroglia
/
Neurônios
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
1997
Tipo de documento:
Article