Increasing of Toxoplasma gondii (Coccidia, Sarcocystidae) infections by Trypanosoma lewisi (Kinetoplastida, Trypanosomatidae) in white rats.
Rev Biol Trop
; 45(2): 877-82, 1997 Jun.
Article
em En
| MEDLINE
| ID: mdl-9458990
ABSTRACT
To demonstrate that T. lewisi infection increases T. gondii multiplication in white rats, groups of five Wistar or Sprague Dawley rats were inoculated with 10(6) T. lewisi trypomastigotes and four or seven days later infected with Toxoplasma tachyzoites. Host survival time was monitored, and the presence of T. gondii was confirmed in all dead rats by studying peritoneal exudate smears and lung tissue sections stained with haematoxylin-eosin. The presence of Toxoplasma cysts or antibodies was checked in the brain of surviving rats. The increase is observed four days after trypanosome inoculation and is dependent on rat strain, but not on inoculum size or rat age. Humoral and cellular factors may have a role in the increase as has been reported for other experimental infections with African trypanosomes and T. cruzi.
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Base de dados:
MEDLINE
Assunto principal:
Trypanosoma lewisi
/
Toxoplasmose Animal
Limite:
Animals
Idioma:
En
Ano de publicação:
1997
Tipo de documento:
Article