The impact of blood culture reporting and clinical liaison on the empiric treatment of bacteraemia.
J Clin Pathol
; 50(12): 1010-2, 1997 Dec.
Article
em En
| MEDLINE
| ID: mdl-9516883
ABSTRACT
AIMS:
To assess the impact of blood culture results and early clinical liaison on the treatment of patients with bacteraemia.METHODS:
123 patients with significant positive blood cultures were followed over a nine month period in a 620 bed teaching hospital. The impact of early blood culture reporting and clinical liaison on the cost and appropriateness of treatment was assessed.RESULTS:
Empiric treatment was started before the Gram stain result in 107 (87%) patients. Treatment was altered on the basis of the Gram stain result in 39 (36%) of these patients, and on culture and sensitivity results in 53 (50%). The spectrum of antibiotic treatment was narrowed in 58 (54%) of these; 20 (19%) on Gram stain result alone. This resulted in a 42% reduction in daily antibiotic costs in patients who had received empiric treatment. Empiric treatment did not follow the hospital antibiotic policy in 49 (46%) of the patients treated. In patients where empiric treatment was not in accordance with hospital policy, 21 (44%) had an isolate resistant to the empiric treatment used; while in patients who received agents in accordance with hospital policy only one (1.7%) had a resistant isolate (p < 0.05). Patients who died (11 (9%)) were less likely to have received empiric treatment in accordance with the antibiotic policy, although this did not reach statistical significance (p = 0.1).CONCLUSION:
Early reporting of Gram stain results from blood cultures, combined with early clinical liaison, results in more rational and cost effective treatment.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Protocolos Clínicos
/
Bacteriemia
/
Auditoria Médica
/
Antibacterianos
Tipo de estudo:
Guideline
/
Observational_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
1997
Tipo de documento:
Article