Secoiridoid glycosides and an antifungal anthranilate derivative from Gentiana tibetica.
Phytochemistry
; 47(7): 1223-6, 1998 Apr.
Article
em En
| MEDLINE
| ID: mdl-9611826
Repetitive chromatography of the methanol extract of the roots of Gentiana tibetica afforded two new secoiridoid glycosides and a novel antifungal anthranilic acid derivative, together with beta-sitosterol, daucosterol, oleanolic acid, loganic acid, gentiopicroside, sweroside, 2'-(2,3-dihydroxybenzoyl)sweroside, trifloroside, rindoside and macrophylloside A. The structures of the new products were determined mainly by spectroscopic methods as 8-hydroxy-10-hydrosweroside, isomacrophylloside and ethyl N-docosanoylanthranilate. Ethyl N-docosanoylanthranilate inhibited the growth of the human pathogenic fungi Candida albicans and Aspergillus flavus. The taxonomic significance of the constituent is discussed briefly.
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Base de dados:
MEDLINE
Assunto principal:
Plantas Medicinais
/
Piranos
/
Raízes de Plantas
/
Iridoides
/
Ortoaminobenzoatos
/
Glucosídeos
/
Antifúngicos
Tipo de estudo:
Diagnostic_studies
Idioma:
En
Ano de publicação:
1998
Tipo de documento:
Article