Validation of a telephone zygosity questionnaire in twins of known zygosity.
Behav Genet
; 28(3): 159-63, 1998 May.
Article
em En
| MEDLINE
| ID: mdl-9670591
ABSTRACT
The aim of this study was to validate a zygosity questionnaire that can be administered over the telephone. Mothers of same-sexed twins of known zygosity and chronicity between 2 and 31 years of age were interviewed on a nine-item questionnaire. From the answers one unweighted and four weighted indices were computed. As single questions, the mother's opinion and the "two peas in a pod" question differentiated best between monozygotic and dizygotic twins. One independent well-trained observer assessed the zygosity based on the questionnaire and made the correct diagnosis in 96% of the cases. A weighted index of eight similarity questions yielded an accuracy of 98%. This study shows that the zygosity of same-sexed twins more than 2 years old and without gross physical malformation can reliably be determined by a telephone questionnaire with a high accuracy.
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Base de dados:
MEDLINE
Assunto principal:
Gêmeos Dizigóticos
/
Gêmeos Monozigóticos
/
Inquéritos e Questionários
/
Estudos em Gêmeos como Assunto
Tipo de estudo:
Diagnostic_studies
/
Evaluation_studies
Limite:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
1998
Tipo de documento:
Article