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Preparation and dissolution rate of gliquidone-PVP K30 solid dispersions.
Martnez, P; Goñi, M M; Cantera, R G; Martin, C; Dios-Viéitez, C; Martínez-Ohárriz, C.
Afiliação
  • Martnez P; Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Navarra, Pamplona, Spain.
Eur J Drug Metab Pharmacokinet ; 23(2): 113-7, 1998.
Article em En | MEDLINE | ID: mdl-9725467
Solid dispersions of gliquidone in PVP K30 were prepared by the solvent method. These dispersions were characterized using X-ray diffraction. In comparison with the drug alone, the physical mixtures and even more the solid dispersions showed an increase in the dissolution rate. Moreover these solid dispersions were stable during storage.
Assuntos
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Base de dados: MEDLINE Assunto principal: Compostos de Sulfonilureia / Povidona / Hipoglicemiantes Idioma: En Ano de publicação: 1998 Tipo de documento: Article
Buscar no Google
Base de dados: MEDLINE Assunto principal: Compostos de Sulfonilureia / Povidona / Hipoglicemiantes Idioma: En Ano de publicação: 1998 Tipo de documento: Article