[Hemopoiesis in chronic myelomonocytic leukemia]. / Gemopoéz pri khronicheskom mielomonotsitarnom leikoze.
Klin Lab Diagn
; (10): 8-11, 1998 Oct.
Article
em Ru
| MEDLINE
| ID: mdl-9864996
ABSTRACT
Hemopoiesis and functional activity of monocytes were assessed in 30 patients with chronic myelomonocytic leukemia (CMML). Changes in haemogram in CMML are characterized by anemia, thrombocytopenia, normal or increased count of leukocytes with absolute monocytosis and increased count of young granulocytes. Bone marrow hemopoiesis is characterized by enhanced proliferation of cellular elements of granulocytopoiesis and monocytes, suppressed erythropoiesis and megakaryocytopoiesis. Dysplastic changes are most expressed in the erythrocytic stem cells. Studies of lysosomal enzymes showed their increased activity in monocytes of CMML patients.
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Base de dados:
MEDLINE
Assunto principal:
Leucemia Mielomonocítica Crônica
/
Hematopoese
Limite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Ru
Ano de publicação:
1998
Tipo de documento:
Article