A new model to assess tcpO2 changes during heat-dependent vasodilation: preliminary observations.
Clin Hemorheol Microcirc
; 19(3): 235-43, 1998 Nov.
Article
em En
| MEDLINE
| ID: mdl-9874359
ABSTRACT
The transcutaneous pO2 (tcpO2) changes induced by the increase of temperature to 45 degrees C after electrode stabilization at 37 degrees C were continuously recorded. The mathematical analysis of the curve led us to identify three different parameters the half-slope "b" time, the angular "mT" coefficient and the angular "mb" parameter, which are not simply the expression of the maximum vasodilation capacity but mainly of the dynamic response of the microcirculatory system to skin heating. These parameters derived from the computerized mathematical analysis of the curve can be also obtained by a graphical approach with a very good approximation. The angular "mb" coefficient was shown to possess the highest statistical power in discriminating the POAD patients from normal controls. The clinical relevance and the possible pathophysiological meaning of these preliminary observations have to be confirmed.
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Base de dados:
MEDLINE
Assunto principal:
Oxigênio
/
Vasodilatação
/
Monitorização Transcutânea dos Gases Sanguíneos
/
Temperatura Alta
Limite:
Humans
Idioma:
En
Ano de publicação:
1998
Tipo de documento:
Article