Hyaluronate-alginate combination for the preparation of new biomaterials: investigation of the behaviour in aqueous solutions.
Biochim Biophys Acta
; 1426(1): 185-94, 1999 Jan 04.
Article
em En
| MEDLINE
| ID: mdl-9878730
ABSTRACT
With the aim of producing a biomaterial for surgical applications, the alginate-hyaluronate association has been investigated. Crossed techniques were used to assess the existence of polymer interactions in aqueous solutions up to 20 mg/ml. Alginate was obtained from algae and hyaluronate was purified from rooster comb. Viscometry measurements using the capillary technique or the Couette flow, together with circular dichroism investigations, evidenced the moderate significance of interactions between the two polysaccharides in dilute solutions. In addition, the case of more concentrated solutions and containing 20 mg/ml alginate was approached by rheological measurements in the flow mode; the behaviour of the polymer associations appeared as a compromise between those of individual polysaccharides.
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Base de dados:
MEDLINE
Assunto principal:
Materiais Biocompatíveis
/
Alginatos
/
Ácido Hialurônico
Idioma:
En
Ano de publicação:
1999
Tipo de documento:
Article