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Necrolytic Migratory Erythema—A Case Report of Pancreatic Occupying Lesion / 罕见病研究
JOURNAL OF RARE DISEASES ; (4): 427-431, 2023.
Article em Zh | WPRIM | ID: wpr-1004970
Biblioteca responsável: WPRO
ABSTRACT
Glucagonoma is a rare neuroendocrine tumor of α cells of the pancreas. The tumor excessively secretes glucagon and causes glucagonoma syndrome.70%-90% of patients with glucagonoma will develop necrolytic migratory erythema (NME). We reported a patient of glucagonoma syndrome who was presented to the dermatology outpatient clinic with a 2-year-history of recurrent erythema and scaling on the skin migrating throughout the body. A skin biopsy was performed and resulting features matched with NME, whilst imaging examinations suggested a soft tissue density tumor present in the tail of the pancreas with somatostatin receptor expression and laboratory tests found an elevated levels of serum glucagon. After the diagnosis was confirmed, the patient was treated with surgical resection of the glucagonoma and the skin eruptions resolved rapidly in 4 days. Meanwhile, we reviewed relevant literature published in recent years and summarized its clinical characteristics in order to improve its understanding by clinicians, including clinical manifestations, laboratory and imaging examinations, diagnosis and treatments.
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Texto completo: 1 Base de dados: WPRIM Idioma: Zh Ano de publicação: 2023 Tipo de documento: Article
Texto completo: 1 Base de dados: WPRIM Idioma: Zh Ano de publicação: 2023 Tipo de documento: Article