Polycystic ovary syndrome and spontaneous preterm birth / 中华围产医学杂志

ABSTRACT

Polycystic ovary syndrome (PCOS) is the most common endocrinopathy among reproductive-age women, characterized by obesity, insulin resistance, chronic low-grade inflammation, and hyperandrogenemia. Studies have revealed that women with PCOS may experience an increased risk of various adverse pregnancy outcomes, such as gestational diabetes, hypertensive disorders of pregnancy, miscarriages, and preterm births. Preterm birth is an important cause of adverse outcome among perinatal infants. However, due to the complexity of its pathogenesis, the current intervention treatment of preterm birth often yields unsatisfactory results. Recent studies have discovered that women with PCOS have a higher risk of preterm birth than those without, suggesting that PCOS is a risk factor for preterm birth. This article reviews the research progress of PCOS-related preterm birth to offer new insights into the prevention and treatment of preterm birth in women caused by PCOS.