Coexistence of Anti-Hu and Anti-SOX1 Autoantibodies in Atezolizumab-related Encephalitis
Journal of the Korean Neurological Association
; : 48-52, 2024.
Article
em Ko
| WPRIM
| ID: wpr-1044267
Biblioteca responsável:
WPRO
ABSTRACT
Although immune checkpoint inhibitor-related encephalitis has been reported, its underlying mechanism and treatment strategies remain unclear. Here, we present the case of a 60-yearold male patient with small cell lung cancer who developed autoimmune encephalitis during treatment with atezolizumab. Notably, this case involved the concurrent detection of two paraneoplastic autoantibodies (anti-Hu and anti-SOX1). Encephalitis was treated by discontinuing atezolizumab and administering steroids, despite the persistence of the antibodies. This case provides insights into the interaction between immune checkpoint inhibitors and paraneoplastic autoantibodies.
Texto completo:
1
Base de dados:
WPRIM
Idioma:
Ko
Ano de publicação:
2024
Tipo de documento:
Article