Effect of a Diet with Unrestricted Sodium on Ascites in Patients with Hepatic Cirrhosis
Gut and Liver
; : 355-361, 2012.
Article
em En
| WPRIM
| ID: wpr-119849
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND/AIMS: There has been debate on whether a sodium-restricted diet (SRD) should be used in cirrhotic patients with ascites in China in recent years. The purpose of this study was to compare the effect of sodium-restricted and unrestricted diets on plasma renin activity (PRA), renal blood flow (RBF) and ascites in patients with liver cirrhosis. METHODS: Two hundred cirrhotic patients with ascites were randomly divided into two groups (98 cases in the sodium-unrestricted diet [SUD] group and 102 cases in the SRD group); 95 patients (96.94%) in the SUD group and 97 patients (95.1%) in the SRD group had post-hepatitis B cirrhosis. RESULTS: Blood sodium and RBF were higher in SUD group than in SRD group (p<0.001), while PRA were significantly lower in SUD group than the SRD group 10 days after treatment (p<0.001). Renal impairment caused by low blood sodium was higher in SRD group than in SUD group (p<0.01). Ascites disappeared in higher proportion of patients in SUD group than in SRD group (p<0.001). CONCLUSIONS: SUD can increase the level of blood sodium and RBF, and be beneficial to diuresis and ascite reduction and disappearance.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Plasma
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Ascite
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Circulação Renal
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Sódio
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China
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Renina
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Dieta
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Dieta Hipossódica
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Diurese
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Fígado
Limite:
Humans
País como assunto:
Asia
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article