Biologigic membrane for guided bone regeneration
Journal of the Korean Association of Oral and Maxillofacial Surgeons
; : 17-24, 2004.
Article
em Ko
| WPRIM
| ID: wpr-155835
Biblioteca responsável:
WPRO
ABSTRACT
The purpose of this study was to evaluate the stability and efficacy of biologic membrane made of freeze-dried cartilage as a barrier to facilitate guided bone regeneration in experimental non-healing bone defects in the rat mandible. Nine adult Sprague-Dawley rats (400-500g) were used in experiment. 5.0mm in diameter were created on the mandibular angle area by means of slow-speed trephine drill. In microscopic examination, dynamic immature bone forming at 2 weeks and its calcification at 4 weeks were observed. The membrane made of lyophilized cartilage taken from human costal cartilage seems to be very effective for guided bone regeneration as a biologic membrane and the scaffold for attachment of cells or local drug delivery system of growth factor, which may meet the ideal requirement of a barrier membrane and graft materials.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Regeneração Óssea
/
Cartilagem
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Sistemas de Liberação de Medicamentos
/
Ratos Sprague-Dawley
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Transplantes
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Mandíbula
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Membranas
Limite:
Animals
/
Humans
Idioma:
Ko
Ano de publicação:
2004
Tipo de documento:
Article