A Case of Cicatricial Alopecia Associated with Erlotinib
Annals of Dermatology
; : S350-S353, 2011.
Article
em En
| WPRIM
| ID: wpr-165612
Biblioteca responsável:
WPRO
ABSTRACT
Erlotinib is a small-molecule tyrosine kinase inhibitor (TKI) of the epidermal growth factor receptor (EGFR). Erlotinib has been used primarily to treat non-small cell lung cancer. In addition to its role in tumor cells, EGFR is also an important regulator of growth and differentiation in the skin and hair. Therefore, EGFR-TKIs have been associated with a number of cutaneous side effects including follicular acneiform eruptions, cutaneous xerosis, chronic paronychia, desquamation, seborrheic dermatitis, and hair texture changes. Herein, we report a rare case of a 61-year-old woman who was treated with erlotinib and experienced cicatricial alopecia.
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Texto completo:
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Base de dados:
WPRIM
Assunto principal:
Paroniquia
/
Quinazolinas
/
Pele
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Proteínas Tirosina Quinases
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Erupções Acneiformes
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Dermatite Seborreica
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Carcinoma Pulmonar de Células não Pequenas
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Alopecia
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Receptores ErbB
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Cloridrato de Erlotinib
Limite:
Female
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Humans
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article