The Effects of ADCON(R)-L on the Adhesion after Strabismus Surgery
Journal of the Korean Ophthalmological Society
; : 208-214, 2003.
Article
em Ko
| WPRIM
| ID: wpr-167743
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE: We investigated the effectiveness of ADCON-L in reducing the formation of adhesion after strabismus surgery in a rabbit model. METHODS: Bilateral recessions of superior rectus muscle (SR) were performed on 18 rabbits. ADCON-L was applied beneath and over the SR in 9 rabbits, while operative fields in the others were irrigated with a balanced salt solution (BSS). The degree of adhesion was recorded at 3 weeks postoperatively. All eyes were enucleated and histopathologic examination was done at 4 weeks postoperatively, and the degree of fibrous proliferation and inflammation were evaluated. RESULTS: A significant reduction in the degree of adhesion and fibrosis was noted in eyes treated with ADCON-L as compared with in those irrigated with BSS (p=0.003, p=0.028). However there was no statistical significance in the degree of inflammation between two groups (p=0.114). CONCLUSIONS: This study suggests that ADCON-L is effective in reducing postoperative adhesion for as long as 4 weeks after strabismus surgery in rabbits.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Fibrose
/
Estrabismo
/
Inflamação
Limite:
Animals
Idioma:
Ko
Ano de publicação:
2003
Tipo de documento:
Article