Influence of Gallamine Triethiodide on the Intraocular Pressure in Man during General Anesthesia / 대한마취과학회지

ABSTRACT

The purpose of this experiment was to evaluate the effect of gallamine triethiodide on the intraocular pressure during general anesthesia for intraocular surgery. Twenty patients in the American Society of Anesthesiologists, physical status l and ll, ages from 15 to 65 yeart with no eye or kidney diseases were studied during anesthesia for elective surgery. All were premedicated with 50mg of meperideine and 0.4mg of atropine. Before induction intraocular pressure was measured under topical anesthesia with 0.5% tetracaine in the eye control value determined. Anesthesia was induced with 5mg/kg of 2.5% thiopental and 1mg/kg of succinylcholine. The intraocular pressure was measured after endotracheal intubation. Anesthesia was maintained with 2mg/kg of meperidine, nitrous oxide and oxygen. On the return of spontaneous respiration following succinylcholine, 2mg/kg of gallamine triethlodide was administered. Subsequent measurements were made 10 and 20 minutes after gallamine triethiodide administration, respectively. The results were as follows: 1) Succinylcholine caused a significant rise in intrascocular pressure. 2) Gallamine triethiodide caused a slight decrease in intraocular pressure 10 and 20 minutes after administration.