Renal Dysfunction in Acute Heart Failure
Korean Circulation Journal
; : 565-574, 2011.
Article
em En
| WPRIM
| ID: wpr-181358
Biblioteca responsável:
WPRO
ABSTRACT
During treatment of acute heart failure (AHF), worsening renal function is often complicated and results in a complex clinical course. Furthermore, renal dysfunction is a strong independent predictor of long-term adverse outcomes in patients with AHF. Traditionally, the predominant cause of renal dysfunction has been attributed to impairment of cardiac output and relative underfilling of arterial perfusion. Recently, emerging data have led to the importance of venous congestion and elevated intra-abdominal pressure rather than confining it to impaired forward cardiac output as the primary driver of renal impairment. Relief of congestion is a major objective of AHF treatment but therapy is still based on the administration of loop diuretics. The results of the recently performed controlled studies for the assessment of new treatments to overcome resistance to diuretic treatment to protect kidneys from untoward effects have been mostly neutral. Better treatment of congestion in heart failure remains a major problem.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Perfusão
/
Débito Cardíaco
/
Estrogênios Conjugados (USP)
/
Inibidores de Simportadores de Cloreto de Sódio e Potássio
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Síndrome Cardiorrenal
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Coração
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Insuficiência Cardíaca
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Hiperemia
/
Rim
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article