Polyuria with the Concurrent manifestation of Central Diabetes Insipidus (CDI) & Type 2 Diabetes Mellitus (DM)
Electrolytes & Blood Pressure
; : 26-30, 2012.
Article
em En
| WPRIM
| ID: wpr-184820
Biblioteca responsável:
WPRO
ABSTRACT
We report a rare case of the concurrent manifestation of central diabetes insipidus (CDI) and type 2 diabetes mellitus (DM). A 56 year-old man was diagnosed as a type 2 DM on the basis of hyperglycemia with polyuria and polydipsia at a local clinic two months ago and started an oral hypoglycemic medication, but resulted in no symptomatic improvement at all. Upon admission to the university hospital, the patient's initial fasting blood sugar level was 140 mg/dL, and he showed polydipsic and polyuric conditions more than 8 L urine/day. Despite the hyperglycemia controlled with metformin and diet, his symptoms persisted. Further investigations including water deprivation test confirmed the coexisting CDI of unknown origin, and the patient's symptoms including an intense thirst were markedly improved by desmopressin nasal spray (10 microg/day). The possibility of a common origin of CDI and type 2 DM is raised in a review of the few relevant adult cases in the literature.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Poliúria
/
Sede
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Privação de Água
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Glicemia
/
Jejum
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Diabetes Insípido Neurogênico
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Desamino Arginina Vasopressina
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Diabetes Mellitus Tipo 2
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Dieta
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Polidipsia
Limite:
Adult
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Humans
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article