A Case of Polyarteritis Nodosa Mimicking Systemic Lupus Erythematosus / 대한류마티스학회지

ABSTRACT

Polyarteritis nodosa (PAN) is a rare systemic necrotizing vasculitis involving multiple organ system. Systemic lupus erythematousus (SLE) also presented as a vasculitic symptoms. So, systemic vasculitis and SLE share some clinical features. We report a case of polyarteritis nodosa mimicking SLE. A 45-year-old woman was admitted due to oliguria. She diagnosed SLE because of pericardial effusion, hemolytic anemia, proteinuria, hematuria, and positivity of anti-dsDNA antibody. But she re-diagnosed as PAN through renal angiography and renal biopsy afterwards. She was treated with high dose steroid, cyclophosphamide, and anti-TNF-alpha antibody, but didn't respond those therapies.