One case of correlation between the human herpesvirus 7 DNA load and the hemo hagocytic syndrome / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
; (6): 123-125, 2011.
Article
em Zh
| WPRIM
| ID: wpr-231174
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To research the relationship between human herpesvirus 7 (HHV-7) viral Load and the etiopathogenisis of hemophagocytic syndrome, in order to provide evidence for the clinical diagnosis of hemophagocytic syndrome and anti-virus therapy.</p><p><b>METHODS</b>Peripheral blood of patient with hemophagocytic syndrome during different treatment periods, extracted DNA, Syntheticed the primers of HHV-7, gene sequence of PCR amplified fragments detected, determined HHV-7 viral Load by Real-time fluorescent quantitative PCR and the ferritin concentration in peripheral blood detected by chemiluminescence.</p><p><b>RESULT</b>The sequence result indicated that PCR amplified fragment was a part of HHV-7 gene, the ferritin concentration viried with the load of HHV-7.</p><p><b>CONCLUSION</b>The occurrence of hemophagocytic syndrome is connetted with the load of HHV-7.</p>
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Fisiologia
/
Virologia
/
Herpesvirus Humano 7
/
Carga Viral
/
Linfo-Histiocitose Hemofagocítica
/
Ferritinas
/
Genética
/
Metabolismo
Limite:
Humans
Idioma:
Zh
Ano de publicação:
2011
Tipo de documento:
Article