Clinical efficacy of tissue adhesive on intractable bleeding during endoscopic submucosal dissection / 中华胃肠外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the efficacy of tissue adhesive on intractable bleeding during endoscopic submucosal dissection(ESD) and delayed bleeding.</p><p><b>METHODS</b>A total of 9874 patients with gastrointestinal mucosal or submucosal tumors underwent ESD in our center from September 2006 to August 2013 and intractable bleeding occurred during ESD in 5 cases. Under the condition of no effective hemostasis methods, the tissue adhesive injection or spray were used to stop the bleeding. The efficacy and safety were evaluated.</p><p><b>RESULTS</b>All the 5 cases were successfully managed by the hemostasis method with tissue adhesive without any adverse event. In follow-up of two months after operation, wound healing and scar formation were observed under endoscopy.</p><p><b>CONCLUSION</b>Tissue adhesive is safe, effective and fast for intractable bleeding during ESD and delayed bleeding.</p>