Clinical analysis of 185 patients with polycythemia vera / 中华血液学杂志
Chinese Journal of Hematology
; (12): 578-580, 2002.
Article
em Zh
| WPRIM
| ID: wpr-261397
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To understand the clinical feature and natural course of polycythemia vera (PV).</p><p><b>METHODS</b>The clinical symptoms, signs, laboratory examination and prognosis of 185 patients with PV were analysed.</p><p><b>RESULTS</b>There are 122 males and 63 females. The mean age was (52.7 +/- 14.1) years. The mean hemoglobin level was (208.3 +/- 21.2) g/L. Pancytosis was displayed in 74 (40%) cases, excess of red blood cells in 33 (17.8%), excess of red blood cells and granulocytes in 67 (36.2%) and excess of red blood cell and platelets in 11 (5.9%). Splenomegaly was found in 123 (66.5%) patients and hepatomegaly in 30 (16.2%). Quantitative assess of serum Epo was done in 25 patients. The level was low in 16 (64.2%) and normal in 9 (36.0%). Hematopoietic progenitor culture yields was elevated in 11 patients, endogenous erythroid colonies (EEC) formation was found in 10 cases (90.9%). Eighty two patients (44.3%) had 101 attacks of vascular thrombotic incidents, 7 patients developed myelofibrosis (MF). Secondary cancer occurred in 1 patient. Two patients died of thrombosis.</p><p><b>CONCLUSION</b>PV is an elderly adult myeloproliferative disease with a high frequency of thrombosis. EEC can be found out in PV patients. The serum Epo level is not increased in PV patients. The main sequelae of PV is MF.</p>
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Base de dados:
WPRIM
Assunto principal:
Patologia
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Policitemia Vera
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Esplenomegalia
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Trombose
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Sangue
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Hemoglobinas
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Contagem de Eritrócitos
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Mielofibrose Primária
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Hepatomegalia
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Contagem de Leucócitos
Limite:
Adult
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Aged
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Female
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Humans
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Male
Idioma:
Zh
Ano de publicação:
2002
Tipo de documento:
Article