Expression of SSX2 gene in human urologic neoplasms / 中华外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the expression of SSX(2)gene in human renal cell carcinoma and urinary transitional cell carcinoma.</p><p><b>METHODS</b>Reverse-transcription polymerase chain reaction (RT-PCR) was used for detecting SSX(2) gene in the specimens from renal cell carcinoma (n = 26), urinary transitional cell carcinoma (n = 27) and in 15 specimens taken from the tumor surrounding tissues.</p><p><b>RESULTS</b>Positive expression of SSX(2) gene at mRNA was detected in 69% renal cell carcinomas (18/26), in 81% urinary transitional cell carcinomas (22/27). The mRNA of SSX(2) was not detected in the 15 specimens from tumor surrounding tissues.</p><p><b>CONCLUSION</b>The SSX(2) gene is highly expressed in human renal cell carcinoma and urinary transitional cell carcinoma.</p>