Photodynamic Therapy for Chronic Central Serous Chorioretinopathy: Multicenter Study of 65 Cases
Journal of the Korean Ophthalmological Society
; : 390-398, 2009.
Article
em Ko
| WPRIM
| ID: wpr-26839
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE:
To determine the effect of photodynamic therapy (PDT) on patients with chronic central serous chorioretinopahty (CSC).METHODS:
This was a retrospective multicenter study. We collected demographic and ophthalmic data for patients with chronic CSC who were treated with PDT from 16 institutions in Korea. The best corrected visual acuity (BCVA), ophthalmoscopic finding and optical coherence tomography at baseline and follow-up visits were compared longitudinally.RESULTS:
Sixty-five eyes of 65 patients were recruited. Males (51 patients, 78.5%) outnumbered females (14 patients, 21.5%). The mean age was 46.4+/-10.0 years of age (28~69). By 1 month, mean BCVA improved from 0.47 to 0.37 (logarithm of the minimum angle of resolution) (P <0.01). This BCVA increased throughout 6 months. Subretinal fluid resolved partially or completely in 89.1% of the patients. Central macular thickness (CMT) decreased from 303.4 to 168.7 micrometer. The amount of change in CMT after PDT was correlated to the female sex and prePDT CMT. At 3 months after PDT, the amount of change in BCVA was significantly related to that of change of CMT (p <0.05). Adverse events were reported in 4 cases, however, most were mild.CONCLUSIONS:
PDT was effective and safe for treating chronic CSC.Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Fotoquimioterapia
/
Triazenos
/
Acuidade Visual
/
Estudos Retrospectivos
/
Seguimentos
/
Tomografia de Coerência Óptica
/
Olho
/
Líquido Sub-Retiniano
/
Coreia (Geográfico)
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Female
/
Humans
/
Male
País como assunto:
Asia
Idioma:
Ko
Ano de publicação:
2009
Tipo de documento:
Article